Helicobacter pylori and reflux disease
نویسندگان
چکیده
منابع مشابه
Helicobacter pylori and gastroesophageal reflux disease
PURPOSE OF REVIEW The purpose of the review is to discuss key studies conducted on the intriguing relationship between Helicobacter pylori and gastroesophageal reflux disease. RECENT FINDINGS Epidemiological studies have repeatedly described a negative association between H. pylori infection and erosive esophagitis, Barrett's esophagus, and esophageal adenocarcinoma, but not between H. pylori...
متن کاملHelicobacter pylori, proton pump inhibitors and gastroesophageal reflux disease.
Proton pump inhibitors have become of pivotal importance for the treatment of GERD. The purpose of this paper is to review the interaction between Helicobacter pylori and PPIs in the treatment of GERD. H. pylori exaggerates the acid suppressive effects of PPIs. During treatment with these drugs, H. pylori-positive subjects thus have a higher intragastric pH than H. pylori-negative subjects. The...
متن کاملGastro-oesophageal reflux disease and Helicobacter pylori: an intricate relation.
Heartburn is a common symptom affecting 21-44% of the adult population on a monthly basis. Oesophagitis is less common, affecting 2% of individuals. Epidemiological studies have shown that patients with gastro-oesophageal reflux disease (GORD) have similar incidence rates of Helicobacter pylori infection as do controls. Some groups have reported that there is a lower incidence, deducing that in...
متن کاملEffects of Helicobacter pylori eradication on gastroesophageal reflux disease.
BACKGROUND AND AIMS Helicobacter pylori infection appears to be a protective factor for gastroesophageal reflux disease (GERD). However, H. pylori is associated with the subtype of esophageal carcinoma, and long-term proton-pump inhibition usage would cause gastric atrophy in patients with persistent H. pylori infection, which is a precancerous lesion. The relationship between H. pylori infecti...
متن کاملDoes Helicobacter pylori infection contribute to gastroesophageal reflux disease?
Helicobacter pylori organisms that infect the stomach conceivably could contribute to esophageal inflammation in patients with gastroesophageal reflux disease (GERD) through any of at least three potential mechanisms: 1) by causing an increase in gastric acid secretion; 2) by spreading to infect the gastric-type columnar epithelium that occasionally can line the distal esophagus; and/or 3) by s...
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ژورنال
عنوان ژورنال: Alimentary Pharmacology & Therapeutics
سال: 2003
ISSN: 0269-2813
DOI: 10.1046/j.1365-2036.2003.01428.x